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Medical News Too Many Patients Get Liver Tests They Don’t Need, Which Can Raise Fears and Costs, Research Shows Doctors are ordering too many liver-related blood tests at the same time, new research shows, which may lead to unneeded worry, biopsies and costs. Instead of “overtesting”, the researchers say, doctors should exclude common liver issues before t... – Michigan Medicine - University of Michigan Journal of Hospital Medicine, March 2017; Journal of Hepatology, February 2017 Embargo expired on 02-Mar-2017 at 00:05 ET Scientists Discover Metabolic Pathway That Drives Tumor Growth in Aggressive Cancers Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic optio... – Mount Sinai Health System Cancer Discovery, March-2017 Embargo expired on 02-Mar-2017 at 06:05 ET Newly Discovered Vulnerability in an Aggressive Breast Cancer Provides Therapeutic Target • Triple-negative breast cancer quickly becomes resistant to current therapies, leaving patients no therapeutic options. • BIDMC researchers discovered that TNBC cells increase production of pyrimidine nucleotides in response to traditional chem... – Beth Israel Deaconess Medical Center Cancer Discovery Embargo expired on 02-Mar-2017 at 00:05 ET Powerful RNA-Based Technology Could Help Shape the Future Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins tha... – Perelman School of Medicine at the University of Pennsylvania Takeda Pharmaceuticals New Frontier Science award; Nature Communications; National Institute of Health (R01-AI050484); National Institute of Health (R01-AI084860); National Institute of Health (P30-AI045008)... Embargo expired on 02-Mar-2017 at 05:00 ET Scientists Wage Fight Against Aging Bone Marrow Stem Cell Niche As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal EMBO that the bone marrow nich... – Cincinnati Children's Hospital Medical Center EMBO March 2, 2017 Embargo expired on 02-Mar-2017 at 06:00 ET How Can We Predict Whose MS Will Worsen? In older people with MS, having fatigue and limited leg function is more often seen in people with MS progression than in those without, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 6... – American Academy of Neurology (AAN) Embargo expired on 01-Mar-2017 at 16:00 ET Benign Paroxysmal Positional Vertigo: Experts Update Best Practices for Diagnosis and Treatment The Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update) provides evidence-based recommendations for healthcare providers on diagnosis and treatment of benign paroxysmal positional vertigo (BPPV) as well as important patient inf... – American Academy of Otolaryngology - Head and Neck Surgery Otolaryngology-Head and Neck Surgery March-2017 Embargo expired on 01-Mar-2017 at 14:00 ET Study: Wireless Stimulation May Ease Migraine Pain as Well as Drugs A preliminary study suggests that a new, wireless patch that you wear on your arm may help reduce migraine pain as well as drugs. The study is published in the March 1, 2017, online issue of Neurology®, the medical journal of the American Academy of... – American Academy of Neurology (AAN) Neurology Embargo expired on 01-Mar-2017 at 16:00 ET Intestinal Bacteria Alter Gut and Brain Function: McMaster Study The goal of the study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice. Using fecal transplants, researchers transferred microbiota from IBS patients w... – McMaster University Embargo expired on 01-Mar-2017 at 14:00 ET In Cleaning Up Misfolded Proteins, Cell Powerhouses Can Break Down Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbag... – Johns Hopkins Medicine Nature; R35GM118172 Embargo expired on 01-Mar-2017 at 13:00 ET MD Anderson Study Ties Protein ‘Reader’ ENL to Common Leukemia Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of l... – University of Texas M. D. Anderson Cancer Center Embargo expired on 01-Mar-2017 at 13:00 ET Monoclonal Antibody Drug Superior to Chemotherapy for Advanced Acute Lymphoblastic Leukemia A Phase III clinical trial involving 101 centers in 21 countries revealed the monoclonal antibody blinatumomab to be more effective than standard chemotherapy for treatment of advanced acute lymphoblastic leukemia (ALL). Study findings were published... – University of Texas M. D. Anderson Cancer Center New England Journal of Medicine Embargo expired on 01-Mar-2017 at 17:00 ET Absent Tumor-Suppressors Allow Melanoma to Thwart Immunotherapy It’s what’s missing in the tumor genome, not what’s mutated, that thwarts treatment of metastatic melanoma with immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in Science Translational... – University of Texas M. D. Anderson Cancer Center Embargo expired on 01-Mar-2017 at 14:00 ET Morgan Stanley Children’s Hospital at NewYork-Presbyterian/Columbia Designated as Level I Trauma Center by the American College of Surgeons The pediatric trauma center at Morgan Stanley Children’s Hospital of NewYork-Presbyterian/Columbia University Medical Center has been verified as a Level I Pediatric Trauma Center by the American College of Surgeons (ACS). – New York-Presbyterian Hospital Embargo expired on 02-Mar-2017 at 06:00 ET A Vulnerability in Triple-Negative Breast Cancer Could Improve Treatment Outcomes Ludwig researchers have shown that triple-negative breast cancer cells ramp up production of a key component of DNA in response to chemotherapy and that targeting this pathway could undermine their resistance to such therapies. – Ludwig Cancer Research Cancer Discovery, Mar-2017 The Three Questions That Can Help Ensure the Success of Treatment for Depression The study found that the patient’s age, expectations regarding the relationship with the therapist, and level of vindictiveness predicted whether they should undergo psychotherapy or medication – University of Haifa Sleep Trackers Can Prompt Sleep Problems Journal article sees potential for unintended effects in their use A 39-year-old man whom we’ll call Mr. R received a sleep-tracking device from his girlfriend. Since starting a new job several years earlier, he sometimes had trouble getting a good... – Rush University Medical Center Brain-Machine Interfaces: Bidirectional Communication at Last Since the early seventies, scientists have been developing brain-machine interfaces; the main application being the use of neural prosthesis in paralyzed patients or amputees. – Université de Genève (University of Geneva) Neuron Mobilizing Health Care Local study suggests urban mobile clinics may help boost patient participation, engagement in care – Harvard Medical School Exploring the Cause of Chronic Lung Transplant Rejection, in a Quest to Stop It A new paper from Michigan Medicine researchers examined the scarring process in transplanted lungs in hopes of identifying novel therapies to stop scarring before it starts. – Michigan Medicine - University of Michigan Journal of Clinical Investigation Few Heart Attack Survivors Get Recommended Physical Activity Researchers have found that only 16 percent of heart attack survivors get the recommended amount of physical activity in the weeks after hospitalization, despite evidence that physical activity reduces the risk of having a second heart attack. – Columbia University Medical Center Journal of the American College of Cardiology, Feb-2017 Tax on Driving Leads to Improved Respiratory Health in Children When Stockholm, Sweden, introduced a “congestion tax” to discourage driving in the center of town, traffic eased and the pollution level dropped by between 5 and 10 percent. The rate of asthma attacks among local children decreased by nearly 50 p... – Johns Hopkins University Carey Business School Dairy Intake May Impact Risk of Breast Cancer, Reports Roswell Park Team • Dairy consumption appears to lower risk for breast cancer • High consumption of yogurt linked to reduced risk of breast cancer • Higher intake of some cheeses tied to slightly increased risk – Roswell Park Cancer Institute Desk Jobs Are Bad for Your Heart and Your Waist A new study shows further evidence for the view that spending too much time sitting down is bad for our health and our waistline. – University of Warwick Women Need to Be Empowered to Take on Shared Decision-Making for Breast Cancer Treatment Most women want to be involved in shared decision-making with oncologists when faced with treatment decisions for breast cancer, a new study from Leeds Beckett University has found. – Leeds Beckett University Neither Increased Access to Surgery Nor Reduced Costs Achieved in States That “Opt-Out” of Requiring Physician Supervision for Anesthesia “Opting-out” of the Medicare rule that requires anesthesia to be administered with physician supervision has little or no impact on access to either inpatient or outpatient surgery, according to a study published in Health Economics Review. – American Society of Anesthesiologists (ASA) Highly Prevalent Gene Variants in Minority Populations Cause Kidney Disease A team engineered mice with the G1 and G2 APOL1 gene mutations that cause human-like kidney disease to study these gene variants found almost exclusively in people of West African descent. These mutations carry an increased risk of kidney disease. Th... – Perelman School of Medicine at the University of Pennsylvania DK105821, T32-DK007006 Americans Divided on Obamacare Repeal, Poll Finds As House Republicans labor to define a new plan to replace the Affordable Care Act (Obamacare), public support for the 2010 legislation is at an all-time high, according to a national survey taken in January by researchers at Washington University in... – Washington University in St. Louis Allergies? Probiotic Combination May Curb Your Symptoms, New Study Finds As we head into allergy season, you may feel less likely to grab a hanky and sneeze. That’s because new University of Florida research shows a probiotic combination might help reduce hay fever symptoms, if it’s taken during allergy season. – University of Florida Cholesterol-Processing Enzyme Protects From Debilitating Brain Lesions Researchers from Case Western Reserve University School of Medicine, the National Institute of Standards and Technology, and Karolinska Institute in Sweden discovered that a specific enzyme in the brain could reduce the formation of debilitating brai... – Case Western Reserve University Journal of Biological Chemistry, March-2017; GM62882; EY11373 Ovarian Cancer Target Molecule May Be Key to Blocking Its Spread Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research at the University of Illinois at Chicago. – University of Illinois at Chicago Oncogene Scientists Stimulate Immune System, Stop Cancer Growth A chemical found in tumors may help stop tumor growth, according to a new study. Researchers at the University of Illinois at Chicago report that increasing expression of a chemical cytokine called LIGHT in mice with colon cancer activated the immune... – University of Illinois at Chicago Cancer Research Multicenter Study Finds No Benefit to Treating Mild Thyroid Dysfunction During Pregnancy A large national study suggests that treating pregnant women for mildly low thyroid function does not improve the IQs of their babies or reduce preterm births or other negative outcomes. – UT Southwestern Medical Center The New England Journal of Medicine, Mar-2017 Groundbreaking Technology Successfully Rewarms Large-Scale Tissues Preserved at Very Low Temperatures University of Minnesota researchers have discovered a groundbreaking process to successfully rewarm large-scale animal heart valves and blood vessels preserved at very low temperatures. The discovery is a major step forward in establishment of tissue... – University of Minnesota College of Science and Engineering Science Translational Medicine New Treatment Delivery Methods of Medication for Opioid Addiction Show Promise Addiction medicine expert Petros Levounis says a maintenance treatment that combines medication with behavioral treatment and recovery support gives patients the best chance of sustainable recovery – Rutgers University Interventional Radiology Registry Launches, Benefits Patient Care Through participation in the new Interventional Radiology (IR) Registry, interventional radiologists can take steps to improve quality of care and outcomes for patients undergoing image-guided interventional procedures. – American College of Radiology (ACR) German Translation Now Available for NCCN Guidelines for Patients: Kidney Cancer The National Comprehensive Cancer Network® (NCCN®), through funding from the NCCN Foundation® and Kidney Cancer Association, has published a German translation of the NCCN Guidelines for Patients®: Kidney Cancer. – National Comprehensive Cancer Network® (NCCN®) Getting to the Root of the Problem by Targeting Cancer Stem Cells A research team comprised of members from The University of Kansas Cancer Center, Stowers Institute for Medical Research, and Children’s Mercy are looking at ways to target cancer stem cells to ensure that once a cancer patient goes into remission,... – University of Kansas Cancer Center New Micro-Pump Technology May Offer Glaucoma Patients an Alternative to Eye Drops It is no secret that the issues associated with current glaucoma medications can be problematic. Systemic medications carry the risk of side effects, while the current medical treatment of choice, eye drops, has its own drawbacks. Studies show that h... – Glaucoma Research Foundation Gene Therapy to Fight a Blood Cancer Succeeds in Major Study An experimental gene therapy that turns a patient's own blood cells into cancer killers worked in a major study. Article by the Associated Press. – Yale Cancer Center Associated Press (AP) In-House Specialty Pharmacy Reduces Medical Errors, Wait Time Dr. Kerin Adelson discusses the in-house specialty pharmacy at Smilow Cancer Hospital with HemeOnc Today – Yale Cancer Center Quality Care Symposium; HemeOnc Today Mayo Clinic Monthly News Tips — February 2017 1) Paper, Paper, Paper, and all those little black dots! 2) Mayo Clinic physician-researchers honored by national society 3) Mayo Clinic National Health Checkup shows African-Americans significantly more concerned about heart health... – Mayo Clinic Two New Devices Enhancing Treatment for Certain Cardiovascular Problems A miniaturized pacemaker that doesn’t have any wires and a coronary stent that gradually dissolves in the body – both approved by Food and Drug Administration within the past year – are being put to good use by heart and vascular specialists. Expert Available – Wake Forest Baptist Medical Center FSMB Workgroups Prepare for Future of Medical Regulation Dr. Chaudhry (FSMB President and CEO) sits down with Dr. Daniel Gifford, Immediate Past Chairman of the FSMB Board of Directors and Chair of the Workgroup on FSMB’s Model Policy on the Use of Opioid Analgesics in the Treatment of Chronic Pain. Drs.... – Federation of State Medical Boards (FSMB) Philadelphia Research Consortium Launched to Speed Access to Preclinical Research Capabilities Across Philadelphia’s Life Sciences Community The Wistar Institute, together with many regional academic institutions driving life sciences discoveries, has launched the Philadelphia Research Consortium – a preclinical research network for facilitating easy access to our region’s robust rese... – Wistar Institute AACC Honors 2017 Award Winners for Advancing Laboratory Medicine and Patient Care AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce the recipients of the 2017 AACC and AACC Academy Awards. Through this annual awards program, AACC and its a... – American Association for Clinical Chemistry (AACC) Academy of Nutrition and Dietetics Celebrates Its Centennial with New Organizational Vision, Mission and Principles As a part of its Second Century initiative and centennial celebrations, the Academy of Nutrition and Dietetics has established a new vision, mission, principles and strategic direction that will expand the influence and reach of the Academy and the n... – Academy of Nutrition and Dietetics Fred Hutch Announces 2017 Harold M. Weintraub Graduate Student Award Recipients Fred Hutchinson Cancer Research Center today announced the recipients of the Harold M. Weintraub Graduate Student Award, which recognizes the outstanding achievement of graduate studies in the biological sciences. The thirteen award recipients were c... – Fred Hutchinson Cancer Research Center MU Health Care Named to Top ‘150 Great Places to Work’ by Becker’s Hospital Review University of Missouri Health Care has been named one of the “150 Great Places to Work in Healthcare” by the health news publication Becker’s Hospital Review. – University of Missouri Health YCC Researcher Craig Crews Is Recipient of Cancer Research Award Yale scientist Craig M. Crews is the recipient of the 2017 Outstanding Achievement in Chemistry in Cancer Research Award granted by the American Association of Cancer Research (AACR). – Yale Cancer Center Dr. David Benedek Named New Psychiatry Department Chair at ‘America’s Medical School’ Army Colonel (Dr.) David M. Benedek will succeed Dr. Robert J. Ursano, M.D., as chair of the Department of Psychiatry at the Uniformed Services University of the Health Sciences’ (USU) F. Edward Hebert School of Medicine – ‘America’s Medical ... – Uniformed Services University of the Health Sciences (USU) Science News Iowa State University Agronomists Show Nitrogen Fertilizer Feeds Healthy Soil in Corn and Soybean Production New Iowa State University research shows nitrogen fertilizer plays an essential role in maintaining soil carbon in corn and soybean fields. Adequate soil carbon is one of the most important metrics of soil health. – Iowa State University Embargo expired on 01-Mar-2017 at 14:05 ET Magic Cover Crop Carpet? Organic farmers can use a combination of cover crops and no-till methods to improve soil health, suppress weeds, and retain moisture. – American Society of Agronomy (ASA), Crop Science Society of America (CSSA), Soil Science Society of America (SSSA) Embargo expired on 01-Mar-2017 at 13:00 ET Food Subsidies and Taxes Significantly Improve Dietary Choices A new systematic review and meta-analysis finds that lowering the cost of healthy foods significantly increases their consumption, while raising the cost of unhealthy items significantly reduces their intake. – Tufts University Embargo expired on 01-Mar-2017 at 14:00 ET Snowpack Water Hack Don’t forget winter snows when considering the water cycle! The Soil Science Society of America (SSSA) March 1 Soils Matter blog post explains how winter snowpack helps recharge groundwater. – Soil Science Society of America (SSSA) Embargo expired on 02-Mar-2017 at 09:00 ET New Heat-Shield Systems, Preserving Astronaut Vision, Supernova 1987A, and More in the Space News Source The latest in space and astronomy in the Space News Source – Newswise Research Shows Nature Can Beat Back Scientific Tinkering with Genes of Entire Species A University of Kansas researcher and colleagues from Cornell University have revealed daunting challenges to changing the DNA of entire populations of species via the most promising techniques available today to produce “gene drive.” – University of Kansas Genetics Singing Posters and Talking Shirts: UW Engineers Turn Objects Into FM Radio Stations A new technique pioneered by University of Washington engineers enables "singing" posters and "smart" clothing to send audio or data directly to your car’s radio or your smartphone by piggybacking on ambient FM radio signals. – University of Washington 14th USENIX Symposium on Networked Systems Design and Implementation Tweaking Electrolyte Makes Better Lithium-Metal Batteries New research shows adding a pinch of chemical additive to a lithium-metal battery’s electrolyte helps make rechargeable batteries that are stable, charge quickly, and go longer in between charges. – Pacific Northwest National Laboratory Corrective 'Eyeglasses' Now Available For X-Ray Research Facilities A research collaboration designed and built special spectacles, or corrective phase plates, for use at light sources that use high-intensity X-rays to probe matter in fine detail. Nature Communications published the details of the method, developed i... – SLAC National Accelerator Laboratory Seiboth et al., Nature Communications, 01 March 2017 (10.1038/ncomms14623) Concurrent Heat Waves, Air Pollution Exacerbate Negative Health Effects of Each Irvine, Calif., March 1, 2017 – The combination of prolonged hot spells with poor air quality greatly compounds the negative effects of each and can pose a major risk to human health, according to new research from the University of California, Irv... – University of California, Irvine Proceedings of the National Academy of Sciences, Mar-2017 Scientists Discover Magnetic “Persuasion” in Neighboring Metals Summary (1-3 sentences): Certain materials can be swayed by their neighbors to become magnetic, according to a new Argonne study. – Argonne National Laboratory Physical Review X, Nov-2016 Is Anything Tough Enough To Survive on Mars? Two separate investigations determine that microorganisms can survive on the surface of Mars, and deep in its subsurface – University of Arkansas, Fayetteville Planetary and Space Science, Feb-2017; Origins of LIfe and Evolution of Biospheres, Sept-2016 Aging Faces Could Increase Security Risks Images of our faces exist in numerous important databases - driver's license, passport, law enforcement, employment - all to accurately identify us. But can these images continue to identify us as we age? Michigan State University biometrics expert A... – Michigan State University IEEE Transactions on Pattern Analysis and Machine Intelligence, Volume: PP, Issue: 99 LED Lighting May Now Shine Brighter Scientists apprehended the atomic-scale, microscopic mechanism that limits light emission in LED lighting. – Department of Energy, Office of Science Applied Physics Letters 108, 141101 (2016). [DOI: 10.1063/1.4942674] Automated Measurement System Enhances Quality, Reduces Handling in Pu-238 Production Under a collaborative partnership between the National Aeronautics and Space Administration and the Department of Energy, a new automated measurement system developed at DOE’s Oak Ridge National Laboratory will ensure quality production of plutoniu... – Oak Ridge National Laboratory "From Finding Nemo to Finding Patents — Adventures in Biomimetics"