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MITRA-MANDAL GLOBAL NEWS 26-Jan-2017 New Research Shows Internalizing Weight Bias Can Be Detrimental to Health People who internalize weight bias, such as fat-shaming and discrimination, are more likely to have risk factors for heart disease and diabetes, according to a new study published in Obesity, the scientific journal of The Obesity Society (TOS). The ... – Obesity Society Obesity Journal, Feb-2016 Embargo expired on 26-Jan-2017 at 00:00 ET When Do Teens with Food Allergies Take Fewer Risks? More support from friends, family and school was linked to less risk-taking among adolescents and young adults with food allergies, according to a study published in the Journal of Allergy and Clinical Immunology: In Practice. – Ann & Robert H. Lurie Children's Hospital of Chicago Journal of Allergy and Clinical Immunology: In Practice, Jan 26, 2017 Embargo expired on 26-Jan-2017 at 00:00 ET Fat Shaming Linked to Greater Health Risks Body shaming is a pervasive form of prejudice, found in cyber bullying, critiques of celebrities’ appearances, at work and school, and in public places for everyday Americans. People who are battling obesity face being stereotyped as lazy, incompet... – Perelman School of Medicine at the University of Pennsylvania Obesity Embargo expired on 26-Jan-2017 at 00:10 ET Mature Heart Muscle Cells Created in the Laboratory From Stem Cells Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists. – Johns Hopkins Medicine Cell Reports; 2015-MSCRFI-1622, HL-0119012, HL-107153, R01HL111198, R01HD086026 Creative People Sleep More, Later, and Less Well The study compared art students and social science students. The finding: art student sleep more hours, but reported more sleep disturbance and daytime dysfunction – University of Haifa Dangerous Infectious Diseases: Bad News for Main Street, Good News for Wall Street? While infectious diseases may be dangerous for the general public, they are good news for stock market investors and traders, says a new study from the University of Portsmouth. – University of Portsmouth Journal of Financial Markets, DOI: 10.1016/j.finmar.2016.12.003 25-Jan-2017 Drug Compound Halts Alzheimer’s-Related Damage in Mice In some people, the brain protein tau collects into toxic tangles that damage brain cells and contribute to diseases such as Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have found a drug that can lower tau leve... – Washington University in St. Louis Science Translational Medicine, Jan-2017; P50 AG05681; R01NS078398; K08NS074194; R21AG044719-01; P30 NS057105 Embargo expired on 25-Jan-2017 at 14:00 ET Social Environment Has a Sizable Impact on Health and Disease in Mice In humans, social factors may explain ‘missing heritability’ in complex diseases. – PLOS PLOS Genetics Embargo expired on 25-Jan-2017 at 14:00 ET New Clues on the Base of Parkinson’s Disease and Other “Synucleinopathies” Parkinson’s disease (PD) and other “synucleinopathies” are known to be linked to the misfolding of alpha-synuclein protein in neurons. Less clear is how this misfolding relates to the growing number of genes implicated in PD through analysis of... – Whitehead Institute for Biomedical Research Embargo expired on 25-Jan-2017 at 12:00 ET Short Bowel Syndrome Results in Changes to Gene Expression Investigators at Children’s Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome (SBS) using a novel zebrafish model and by performing intensive gene sequencing. This approach to ... – Children's Hospital Los Angeles Saban Research Institute BioMed Central Genomics; 8236-TCS008566; 8237-TGA009320-00 Embargo expired on 25-Jan-2017 at 06:00 ET Repeal All of Obamacare? Primary Care Physicians Not in Favor, Survey Suggests Results of a random sample survey of 426 primary care physicians by a team of researchers found that the majority does not support repealing the Patient Protection and Affordable Care Act in its entirety, and the percentage of those who support compl... – Johns Hopkins Medicine New England Journal of Medicine Embargo expired on 25-Jan-2017 at 17:00 ET More than a Quarter of U.S. Adults, Roughly 9 Percent of U.S. Youth Use Tobacco BUFFALO, N.Y. — More than 1 in 4 adults and nearly 1 in 10 youth use tobacco, according to findings from the Population Assessment of Tobacco and Health (PATH) Study, published online ahead of print in the New England Journal of Medicine. The PATH ... – Roswell Park Cancer Institute Embargo expired on 25-Jan-2017 at 17:00 ET DiGeorge Syndrome Kidney Problems May Be Caused By Missing Gene A research team led by Columbia University has discovered that loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, solving a 60-year-old medical mystery. – Columbia University Medical Center New England Journal of Medicine, January 25, 2017 Embargo expired on 25-Jan-2017 at 17:00 ET Diabetes Drug Takes Aim at Cancer’s Fuel Source To understand how metformin changes the biology of cancer cells, researchers at the Sidney Kimmel Cancer Center at Thomas Jefferson University tested tumor cells before and after metformin treatment in non-diabetic cancer patients. The pilot clinical... – Thomas Jefferson University The Laryngoscope; K08 CA175193-01A1 ; 5P30CA056036-17; 2014 Young Investigator Award from the American Academy of Otolaryngology and American Head and Neck Society Embargo expired on 25-Jan-2017 at 09:00 ET Most Primary Care Doctors “Strongly Endorse” Key Elements of the Affordable Care Act Proponents of repealing the Affordable Care Act, including President Donald Trump’s nominee for Secretary of Health and Human Services, Tom Price, have argued that the law places an undue burden on physicians. However, according to new research, wh... – Perelman School of Medicine at the University of Pennsylvania New England Journal of Medicine Embargo expired on 25-Jan-2017 at 17:00 ET Huntsman Cancer Institute Scientists Identify Bone Degradation Process in Metastatic Breast Cancer Once breast cancer spreads through the body, it can degrade a patient’s healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute (HCI) at the University of Utah have identified a new way that bones get destroyed through can... – University of Utah Health Sciences CA042014; CA166422; W81XWH-08-1-0109 Embargo expired on 25-Jan-2017 at 14:00 ET Should Hypothyroidism in Pregnancy Be Treated? When a woman becomes pregnant, many changes occur in her body. One of those changes is in the levels of various hormones produced by the body. – Mayo Clinic Embargo expired on 25-Jan-2017 at 18:30 ET Fly Growth Mimics Cancer Cells, New Target for Treating Glioblastoma, New Way to Starve Tumors to Death, and More in the Cancer News Source Click here to go directly to the Cancer News Source – Newswise When Should Doctors Treat Short Children and Teens with Growth Hormone? When is it appropriate to treat short children with growth hormone? The answer is not always clear-cut, as many parents and physicians weigh social, medical and ethical concerns. Experts in pediatric endocrinology have issued a new set of guidelines ... – Children's Hospital of Philadelphia Hormone Research in Paediatrics, online Nov. 25, 2016, in print Jan. 2017 Swarthmore Economists Discover That Coupons for Produce Can Boost Healthy Food Purchases In the experiment, economists Erin Todd Bronchetti, Ellen Magenheim, David Huffman, and more than 30 students found that providing coupons for produce at a Chester (Pa.) grocery store led shoppers to spend more total dollars on fresh fruits and veget... – Swarthmore College Clues to Pediatric GI Illness, Delaying Pot Smoking to Age 17 Is Better for Teens' Brains, When Should Doctors Treat Short Children and Teens with Growth Hormone, and More in the Children's Health News Source Click here for the latest research and features on Children's Health. – Newswise Predicting and Preventing Prostate Cancer Spread Australian researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body. The discovery may lead to the development of a blood test that could predict whether cancer will spread from the prostate tumour to oth... – University of Adelaide Cancer Research Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza).... – The Rockefeller University Press Journal of Cell Biology, February 6th, 2017; 21377106; 2015DFM30040; 2015ZX09101009; XDA12020000; 81321092; 81573464 Good Outcomes with 'Telepsychiatry' in Medical Treatment of Opioid Use Disorder For people with opioid use disorder receiving medication treatment with buprenorphine, a telepsychiatry approach—using videoconferencing as an alternative to in-person group sessions—provides similar clinical outcomes, reports a study in the Jour... – Wolters Kluwer Health: Lippincott Williams and Wilkins Journal of Addiction Medicine NYU Researcher Studies Disparities Between Asian Immigrants and Sufficient Access and Utilization of Dental Services The results of the study indicated that the acculturation variable - length of stay in the US - had the strongest association with having a dental visit in the previous twelve months among Asian immigrants. This finding remained significant even afte... – New York University American Journal of Preventive Medicine New Study Shows Anxiety Impairing Quality of Life for Postmenopausal Women Anxiety associated with hot flashes, sleep disruption, and muscle and joint complaints – North American Menopause Society (NAMS) Menopause Imaging Technique Measures Tumor Stiffness to Aid Surgical Planning An important step in planning tumor surgery includes assessing the tumor stiffness to aid in surgical planning. Because tumors within the skull cannot be examined non-invasively, researchers used Magnetic Resonance Elastography (MRE) to assess pituit... – National Institute of Biomedical Imaging and Bioengineering Pituitary, June- 2016; EB001981 New Class of Materials Could Revolutionize Biomedical, Alternative Energy Industries Polyhedral boranes have become the basis for the creation of cancer therapies, enhanced drug delivery and new contrast agents needed for radioimaging and diagnosis. Now, a researcher at the University of Missouri has discovered an entirely new class ... – University of Missouri Health Angewandte Chemie New Guidelines Promote More Family Engagement in Intensive Care Units Having a loved one go through a critical illness is a stressful and traumatic experience that may have lasting effects months after the patient is discharged from the intensive care unit (ICU). To improve the well-being of both patients and family du... – University of California San Diego Health Sciences Critical Care Medicine Delaying Pot Smoking to Age 17 Is Better for Teens' Brains, a New Study Suggests Adolescents who smoke marijuana as early as 14 do worse by 20 on some cognitive tests and drop out of school at a higher rate than non-smokers. But if they hold off until age 17, they're less at risk. – Universite de Montreal Development and Psychopathology, Dec. 29, 2016 FSU Research Links Brain Shape to Personality Differences The shape of your brain can influence personality traits, according to a new study published in the journal Social Cognitive and Affective Neuroscience. – Florida State University Tissue Engineering Advance Reduces Heart Failure in Model of Heart Attack Cardiac muscle patches in this proof-of-concept research may represent an important step toward the clinical use of 3-D-printing technology, as researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold ma... – University of Alabama at Birmingham Circulation Research; CBET-1445650; HL 99507; HL 114120; HL 131017; UO1 134764 Living Without Lungs for Six Day Saves a Mom’s Life In a bold and very challenging move, thoracic surgeons at Toronto General Hospital, University Health Network removed severely infected lungs from a dying mom, keeping her alive without lungs for six days, so that she could recover enough to receive ... – University Health Network (UHN) Shoveling Snow: Winter Chore or Health Hazard? Believe it or not, winter has officially begun! And, although there has been a lack of significant snowfall and cold temperatures in our area, we should still be prepared for the possibility of more seasonable weather. – Valley Health System Breathe Easy as You Plan an Allergy- and Asthma-Free Valentine’s Day If you want to plan the perfect Valentine’s Day for your sweetheart, keep their allergies and asthma in mind. – American College of Allergy, Asthma and Immunology (ACAAI) Understanding Motivations for Behavior Can Be Helpful for Children with Autism For many families, normal activities, such as going to a large family gathering or an amusement park, can be difficult to navigate with a child with autism, as the child may be act out due to being overwhelmed by extra noises and stimulation. To hel... Expert Available – University of Missouri Health 24-Jan-2017 Consumer-Use Baby Monitors Have Little Proven Benefit for Healthy Infants It sounds simple and harmless—an electronic sensor attached to a baby’s sock that monitors vital signs and alerts parents on their smart phones if, for instance, an infant’s oxygen saturation level drops. But pediatric experts argue that such d... – Children's Hospital of Philadelphia JAMA, Jan. 24, 2017 Embargo expired on 24-Jan-2017 at 11:00 ET Parents of Children Born with Heart Defects Crave Disease Stats, Surgeon Info Survival statistics, surgeon-specific experience, and complication rates are the types of information most wanted by parents of children with congenital heart disease, according to a survey released at the 53rd Annual Meeting of The Society of Thorac... – The Society of Thoracic Surgeons Embargo expired on 24-Jan-2017 at 10:00 ET Lung Cancer Screening Programs in Communities Are Vital, but Challenges Exist Implementing lung cancer screening as a high-quality preventive health service in a community setting is feasible, but comes with several key challenges, according to a scientific presentation at the 53rd Annual Meeting of The Society of Thoracic Sur... – The Society of Thoracic Surgeons Embargo expired on 24-Jan-2017 at 10:00 ET Heart Surgery Is Excellent Option for Elderly Patients with Aortic Stenosis Elderly patients with aortic stenosis (AS) and medium surgical risk experienced better than expected results after undergoing traditional surgical aortic valve replacement (SAVR), according to research presented at the 53rd Annual Meeting of The Soci... – The Society of Thoracic Surgeons Embargo expired on 24-Jan-2017 at 10:00 ET Half of Breast Cancer Patients Experience Severe Side Effects Nearly half of women treated for early stage breast cancer reported at least one side effect from their treatment that was severe or very severe, a new study finds. – Michigan Medicine - University of Michigan Cancer; CA163233 Embargo expired on 24-Jan-2017 at 09:00 ET Body Cooling vs. Active Fever Prevention: Similar Outcomes for Children After in-Hospital Cardiac Arrest Emergency body cooling does not improve survival or functional outcomes in children who experience in-hospital cardiac arrest any more than normal temperature control. – Michigan Medicine - University of Michigan Embargo expired on 24-Jan-2017 at 17:30 ET Mindfulness Meditation Training Lowers Biomarkers of Stress Response in Anxiety Disorder Mindfulness meditation is an increasingly popular treatment for anxiety, but testing its effectiveness in a convincing way has been difficult. Now a rigorously designed, NIH-sponsored clinical trial has found objective physiological evidence that min... – Georgetown University Medical Center Psychiatry Research Embargo expired on 24-Jan-2017 at 10:00 ET Deep Brain Stimulation Studies in Alzheimer’s Disease Pose Ethical Challenges Promising, early studies of deep brain stimulation (DBS) for the treatment of Alzheimer’s disease have paved a path for future clinical trials, but there are unique ethical challenges with this vulnerable population regarding decision making and po... – Perelman School of Medicine at the University of Pennsylvania Journal of Alzheimer’s Disease Embargo expired on 24-Jan-2017 at 12:15 ET Critically Ill Children Don't Benefit From Tightest Control of Blood Sugar Critically ill infants and children do not gain extra benefit from control of their blood sugar level to lower levels, compared to higher levels within the usual care range, say researchers who led a national clinical trial. While both levels of bloo... – Children's Hospital of Philadelphia New England Journal of Medicine, Jan. 24, 2017; Society for Critical Care Medicine 2017 annual meeting; HL107681, HL108028 Embargo expired on 24-Jan-2017 at 17:30 ET Study Unveils New Way to Starve Tumors to Death Scientists at Washington University School of Medicine in St. Louis have exploited a common weak point in cancer cell metabolism, forcing tumor cells to reveal the backup fuel supply routes they rely on when this weak point is compromised. Mapping th... – Washington University in St. Louis Cell Reports Embargo expired on 24-Jan-2017 at 12:00 ET Researchers Discover BRCA1 Gene Is Key for Blood Forming Stem Cells Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leuk... – UT Southwestern Medical Center Embargo expired on 24-Jan-2017 at 12:00 ET Partnership to Deliver Safer Football Helmets Announced UAB and VICIS have each made major strides in developing next generation football helmets in response to the growing concussion crisis, and they have partnered to combine expertise and intellectual property to bring more effective helmets to the mark... – University of Alabama at Birmingham Embargo expired on 24-Jan-2017 at 17:00 ET Nutritional Considerations for Healthy Aging, Is Bacon Fit for a Breakfast of Champions, Calorie Restriction Lets Monkeys Live Long and Prosper, and More in the Food Science News Source Click here to go to the Food Science News Source – Newswise Breast Density Research Edges Closer to Cancer Prevention Australian researchers are one step closer to breast cancer prevention after finding a new driver for breast density, an identified risk factor for breast cancer. – University of Adelaide Breast Cancer Research U Study: Law Aiding Infants at Risk for Hearing Loss The study, published Jan. 24, 2017, in Pediatrics, is the first to assess how implementation of a state-wide screening can pick up hearing loss in infants due to congenital cytomegalovirus. – University of Utah Pediatrics, Jan. 24, 2017 Biologists Identify Reproductive "Traffic Cop" University of Iowa researchers have found a protein that regulates how chromosomes pair up and pass genetic information. FDK-6 dictates the speed at which maternal and paternal chromosome strands move and join in roundworms. The findings were publish... – University of Iowa Journal of Cell Biology Penn Researchers Help Unravel Mysteries of Pancreatic Cancer’s Resistance to Standard Therapies In a new study, researchers at the Perelman School of Medicine at the University of Pennsylvania have illuminated one of pancreatic cancer’s major resistance mechanisms: a form of inflammation that is triggered by the tumor in response to treatment... – Perelman School of Medicine at the University of Pennsylvania K08 CA138907; F30 CA196106; F30 CA196124 KU Researchers Find Statins May Hold Keys to Future Cancer Treatment Researchers at The University of Kansas Cancer Center have found that high doses of drugs commonly used to fight high cholesterol can destroy a rogue protein produced by a damaged gene that is associated with nearly half of all human cancers – University of Kansas Cancer Center Nat Cell Bio, Nov-2016 Timing of Chemo Affects Inflammation, Mice Study Suggests COLUMBUS, Ohio – The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests. – Ohio State University Scientific Reports New Models for Validating Computational Simulations of Blood Flow and Damage in Medical Devices A collaborative effort to improve the development of computational fluid dynamics (CFD) methodologies for evaluating "blood contacting" medical devices—receiving the Willem Kollf Award for top abstract at the ASAIO 2016 conference—is now reported... – Wolters Kluwer Health: Lippincott Williams and Wilkins ASAIO Journal Immigration Fears Among Latinos Can Impact Baby Size at Birth With deportation and discrimination fears currently on the minds of many in the United States, a University of Michigan study shows that the stress from an historic immigration raid is associated with Latina mothers delivering babies with lower birth... – University of Michigan Scripps Florida Team Awarded $1.8 Million Grant to Develop Drugs for Heart Disease and Rheumatoid Arthritis Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidat... – Scripps Research Institute 1R01GM122109-01 Natural Compound Found in Herbs, Vegetables Could Improve Treatment of Triple-Negative Breast Cancer in Women Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites. Now, University of Missouri researchers have found that luteolin, a natura... – University of Missouri Health Researchers Discover Potential New Target for Treating Glioblastoma Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O’Donnell Jr. Brain Institute and Har... – UT Southwestern Medical Center Brain Scan Before Antidepressant Therapy May Predict Response A functional MRI brain scan may help predict which patients will respond positively to antidepressant therapy, according to a new study published in the journal Brain. – University of Illinois at Chicago Brain Institute for Autism Research (IAR) at Canisius College Gives Hope to Children with Autism Spectrum Disorder The latest study released by the Institute for Autism Research (IAR) shows more promise that a diagnosis of autism spectrum disorder no longer guarantees a difficult life for children. – Canisius College Journal of Clinical Child and Adolescent Psychology, Dec-2016 Vanderbilt Studies Find Tonsillectomies Offer Only Modest Benefits Removing tonsils modestly reduced throat infections in the short term in children with moderate obstructive sleep-disordered breathing or recurrent throat infections, according to a systematic review conducted by the Vanderbilt Evidence-based Practic... – Vanderbilt University Medical Center Pediatrics New Tuberculosis Therapy Could Be More Potent Than Current Treatments Researchers have devised a potential drug regimen for tuberculosis that could cut the treatment time by up to 75 percent, while simultaneously reducing the risk that patients could develop drug-resistant TB. – University of California, Los Angeles (UCLA), Health Sciences Nature Communications Georgetown Clinical Trial of Nilotinib in Alzheimer’s Disease Begins A clinical trial to examine the effect of nilotinib on clinical outcomes and biomarkers in people with mild to moderate Alzheimer’s disease has opened at Georgetown University Medical Center. – Georgetown University Medical Center Take Heart: AACN Updates Resources for Getting Accurate Cardiac Monitoring Results Cardiac monitoring remains a key element in caring for hospitalized patients who a