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Medical News 09-Jan-2017 Mayo Clinic Researchers Identify New Potential Treatment for Cancer Metastasis Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the U.S. Food and Drug Administration. Mayo Clinic researchers have identified that a key drug target, CDK4/6,... – Mayo Clinic Embargo expired on 09-Jan-2017 at 05:00 ET Bilingualism May Save Brain Resources as You Age A research team established that years of bilingualism change how the brain carries out tasks that require concentrating on one piece of information without becoming distracted by other information. This makes the brain more efficient and economical ... – Universite de Montreal Journal of Neurolinguistics, Otc. 2016 Experiments in Mice May Help Boost Newly FDA-Approved Therapy for Spinal Muscular Atrophy Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy. – Johns Hopkins Medicine Neuron; UL1 TR 001079 UVA Honored Nationally for Bariatric Surgery, Cancer Care University of Virginia Medical Center’s bariatric surgery and cancer care programs have earned 2017 national Women’s Choice Awards from WomenCertified Inc. The UVA Cancer Center earned its America’s Best Hospitals for Cancer Care award based on... – University of Virginia Health System 06-Jan-2017 New Study Highlights the Benefit of the Use of ICD for Reducing Mortality Rate in Patients with Non-Ischemic Cardiomyopathy The UAB study, an updated meta-analysis of the use of implantable cardioverter-defibrillators for non-ischemic cardiomyopathy, provides further support to the current American Heart Association and American College of Cardiology guidelines and challe... – University of Alabama at Birmingham Researchers Find Key Genetic Driver for Rare Type of Triple-Negative Breast Cancer By developing a new mouse model to study a poorly understood protein, researchers uncovered its link to metaplastic breast cancer, opening the door to better understanding of this challenging breast cancer subtype. – University of Michigan Health System Oncogene; CA125577; CA107469; CA196084; GM086262; CA46592 Time-Restricted Feeding Study Shows Promise in Helping People Shed Body Fat For the first time in humans, it has been reported that eating early in the day lessens daily swings in hunger and changes the 24-hour pattern of fat oxidation and energy metabolism, which may aid in weight loss – University of Alabama at Birmingham Lung Cancer Patients May Benefit From Delayed Chemotherapy After Surgery A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers. – Yale Cancer Center Aspirin Use Found to Lower Risk of Pancreatic Cancer The regular use of aspirin lowers the risk for pancreatic cancer by almost 50 percent, a new study in China led by the Yale School of Public Health finds. – Yale Cancer Center Unexpected Role for Epigenetic Enzymes in Cancer In a Yale-led study, Qin Yan and his co-authors focused on a family of enzymes — known as KDM5 — that have been shown in previous studies to be involved in cancer cell growth and spreading. – Yale Cancer Center Vision Problems After Concussion – Special Issue of Optometry and Vision Science Presents New Research Vision problems are a common and sometimes lasting consequence of head injuries—from children and teens with sports-related concussions to military personnel with combat-related traumatic brain injury (TBI). New research and perspectives on TBI and... – Wolters Kluwer Health: Lippincott Williams and Wilkins Optometry and Vision Science Consumption of Grilled Meat Linked to Higher Mortality Risk Among Breast Cancer Survivors Findings indicate that higher consumption of grilled, barbecued, and smoked meat may increase the mortality risk among breast cancer survivors. – Oxford University Press Journal of the National Cancer Institute Tailored Organoid May Help Unravel Immune Response Mystery Cornell and Weill Cornell Medicine researchers report on the use of biomaterials-based organoids in an attempt to reproduce immune-system events and gain a better understanding of B cells. – Cornell University ACS Biomaterials Science & Engineering, Dec. 13, 2016; Nature Protocols Why Is Asthma Worse in Black Patients? African Americans may be less responsive to asthma treatment and more likely to die from the condition, in part, because they have a unique type of airway inflammation, according to a study led by researchers at the University of Illinois at Chicago ... – University of Illinois at Chicago Journal of Allergy and Clinical Immunology Research Reveals Help for Eating Disorder Patients More people are dying from eating disorders than any other psychiatric disorder, and one Cornell College professor has discovered a way to help women by significantly reducing eating disorder symptoms in those who are struggling. – Cornell College Parents Purchase Frozen Dinners for More Than Convenience Processed foods are higher in calories, sugar, sodium, and saturated fat than natural foods, but prepackaged, processed meals remain a popular choice for many consumers because they reduce the energy, time, and cooking skills needed to prepare food. ... – Society for Nutrition Education and Behavior Journal of Nutrition Education and Behavior National Organization of Italian American Women Will Honor Dr. Pat LoRusso The Connecticut Region of the National Organization of Italian American Women (NOIAW) will honor three of Connecticut’s most prominent and pioneering women at its eighth annual Epiphany Celebration brunch and silent auction event, on Sunday, Januar... – Yale Cancer Center Preterm Infants Fare Well in Early Language Development Preterm babies perform as well as their full-term counterparts in a developmental task linking language and cognition, a new study from Northwestern University has found.The study, the first of its kind with preterm infants, tests the relative contri... – Northwestern University Developmental Science New Apps Designed to Reduce Depression and Anxiety as Easily as Checking Your Phone Soon you can seek mental health advice on your smartphone as quickly as finding a good restaurant.A novel suite of 13 speedy mini-apps called IntelliCare resulted in participants reporting significantly less depression and anxiety by using the apps o... – Northwestern University Journal of Medical Internet Research; R01 MH100482 Halting Lethal Childhood Leukemia Northwestern Medicine scientists have discovered the genetic driver of a rare and lethal childhood leukemia and identified a targeted molecular therapy that halts the proliferation of leukemic cells. The finding also has implications for treating oth... – Northwestern University Cell; R35CA197569 Experimental Treatment for Parkinson's Symptoms Shows Promise More than 12 months after Parkinson's patient Bill Crawford received "DBS Plus," he can walk more easily and is back to leading services at his beloved Porter Memorial Church in Lexington, Ky. – University of Kentucky New Rule for MLB Pitchers Could Lead to Fatigue, Muscle Damage Latest Research Highlights from ACSM – American College of Sports Medicine (ACSM) Drug That Improves Blood Flow in Damaged Heart Might Also Fight Breast Cancer Researchers are looking at a drug once used to improve blood flow in damaged hearts in thousands of patients as a possible treatment option for triple negative breast cancer (TNBC). – Houston Methodist Can a Weight Loss Program Result in Physical Activity Improvements Among Older Adults with Type 2 Diabetes? Latest Research Highlights from ACSM – American College of Sports Medicine (ACSM) Frequency of Breaks in Sedentary Time and Postprandial Metabolic Responses Latest Research from ACSM – American College of Sports Medicine (ACSM) 05-Jan-2017 Structure of Kidney Failure Patients’ Blood Clots May Increase Their Risk of Early Death • Hemodialysis patients tend to have denser blood clots than individuals without kidney disease. • Dense blood clots were linked to an increased risk of premature death from cardiovascular and other causes. – American Society of Nephrology (ASN) Embargo expired on 05-Jan-2017 at 17:00 ET Many Kidney Failure Patients Lack Advance Directives Near the End of Life • Among nursing home residents in the last year of life, patients with kidney failure were far less likely to have advance directives that put limitations on treatments and designated surrogate decision makers compared with other nursing home resid... – American Society of Nephrology (ASN) Embargo expired on 05-Jan-2017 at 17:00 ET Police Sobriety Checkpoints Can Reduce Drunk Driving Better Than Increased Penalties Driving while impaired (DWI) causes more than 10,000 deaths per year in the United States. Although enforcing criminal sanctions for DWI is the traditional response, the success of these measures has been inconsistent. This study looked at risk perce... – Research Society on Alcoholism Alcoholism: Clinical and Experimental Research Embargo expired on 05-Jan-2017 at 17:00 ET Buzzing the Vagus Nerve Just Right to Fight Inflammatory Disease Electrical vagus nerve stimulation can help fight inflammatory diseases like Crohn's or arthritis but can also contribute somewhat to inflammation. Engineers have tweaked the buzz to keep the good effects and minimize those less desirable. Their inno... – Georgia Institute of Technology Nature Scientific Reports; Ian’s Friends Foundation; R01EB016407 Embargo expired on 05-Jan-2017 at 10:00 ET The Lancet Diabetes & Endocrinology: Gastric Bypass Helps Severely Obese Teenagers Maintain Weight Loss Over Long Term Gastric bypass surgery helps severely obese teenagers lose weight and keep it off, according to the first long-term follow-up studies of teenagers who had undergone the procedure 5-12 years earlier. However, the two studies, published in The Lancet D... – Cincinnati Children's Hospital Medical Center Embargo expired on 05-Jan-2017 at 18:30 ET How Cancers Evade Immunotherapy, Breast Cancer Test Helps Determine Who Will Benefit From Long-Term Therapy, Implantable Microrobots, and More in the Cancer News Source Click here to go directly to the Cancer News Source – Newswise Cancers Evade Immunotherapy by 'Discarding the Evidence' of Tumor-Specific Mutations Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutati... – Johns Hopkins Medicine Cancer Discovery; CA121113, CA006973, CA180950 La Roche-Posay and the George Washington University Publish Unprecedented International Study on Sun Protection Behavior and Skin Cancer Awareness A large international survey, published in the Journal of the European Academy of Dermatology & Venereology by researchers from La Roche-Posay and the George Washington University, asked nearly 20,000 participants about their sun protection behavior ... – George Washington University January Issue of AACC’s Clinical Chemistry Journal Highlights the Breakthrough Medical Tests That Will Advance Cardiovascular Care Laboratory medicine experts are using a growing understanding of the molecular signatures of heart disease to develop more precise tests for the early diagnosis, monitoring, and targeted treatment of this condition. A special issue of Clinical Chemis... – American Association for Clinical Chemistry (AACC) Clinical Chemistry, Jan-2017 Nerve-Signaling Protein Regulates Gene Associated with Schizophrenia Researchers from the University of California, San Diego, have identified a protein that regulates a gene associated with schizophrenia. The study’s findings have significant implications for schizophrenia treatment. – American Physiological Society (APS) Breaking Research Published in AACC’s Clinical Chemistry Journal Could Reduce Recurrence of Heart Attacks, Death in Patients with Cardiovascular Disease Research published today in AACC’s Clinical Chemistry journal shows that a test can identify patients with a history of cardiovascular disease who are at high risk of another heart attack or death and would benefit from treatment with the drug vora... – American Association for Clinical Chemistry (AACC) Clinical Chemistry, Jan-2017 Novel Tests Published in AACC’s Clinical Chemistry Journal Could Improve Treatment for Heart Failure Patients For the first time, researchers have developed tests that could improve treatment for heart failure patients by diagnosing the condition with greater accuracy, as well as by detecting the onset of congestive heart failure earlier. The findings were p... – American Association for Clinical Chemistry (AACC) Clinical Chemistry, Jan-2017 Graduate Research Explores Glioblastoma Tumor Cells Invasion in 3D Environments Wichita State graduate student Pranita Kaphle is researching the migration of cancer cells in a 3D environment. She is targeting glioblastoma multiforme in the brain, a rapid spreading and aggressive high-grade tumor. Kaphle hopes to pursue a career ... – Wichita State University Immune Cell Therapy Shows Promising Results for Lymphoma Patients, Says Moffitt Researchers TAMPA, Fla. – Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors. The body has two types of lymp... – Moffitt Cancer Center Molecular Therapy, Jan-2017 Vaginal Microbes Point Toward Early Detection and Screening for Endometrial Cancer Endometrial cancer triggers remain elusive, despite continued research. But given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. – Mayo Clinic Optogenetics Breakthrough: UNC Scientists Expand the Use of Light to Control Protein Activity in Cells Scientists at the University of North Carolina School of Medicine have developed a method to control proteins inside live cells with the flick of a switch, giving researchers an unprecedented tool for pinpointing the causes of disease using the simpl... – University of North Carolina Health Care System Science Using Fat to Help Wounds Heal Without Scars Doctors have found a way to manipulate wounds to heal as regenerated skin rather than scar tissue. The method involves transforming the most common type of cells found in wounds into fat cells – something that was previously thought to be impossibl... – Perelman School of Medicine at the University of Pennsylvania DK19525; R01-AR055209; P30-AR057217 Anemia Protects African Children Against Malaria Researchers have found iron deficiency anemia protects children against the blood-stage of Plasmodium falciparum malaria in Africa, and treating anemia with iron supplementation removes this protective effect. – University of North Carolina Health Care System EBioMedicine, Nov-2016 UCI-Penn Study in Science Reveals Natural Process for Scar-Free Wound Healing Irvine, Calif., Jan. 5, 2017 — Scars are often the unwanted and permanent result of wound healing, but University of California, Irvine and University of Pennsylvania researchers have discovered a natural regeneration process that stimulates scar-f... – University of California, Irvine Science, Jan-2017 EU Agrees Dental Amalgam Ban in Children, Pregnant and Breastfeeding Women European civil society has endorsed this week’s provisional agreement by the three EU institutions (European Parliament, European Commission and the Council of the European Union) to ban dental amalgam fillings for children under 15 and for pregnan... – Health and Environment Alliance (HEAL) Regenerative Medicine Is Likely Game Changer for Cardiovascular Disease Regenerative medicine has much to offer the cardiovascular field, although there is still a way to go before it is ready for routine clinical application, according to Andre Terzic, MD, PhD, director of the Mayo Clinic Center for Regenerative Medicin... – American Association for Thoracic Surgery (AATS) The Medical Minute: Taking Control of Back Pain About 80 percent of the population will experience at least one significant episode of back pain in their lifetime. When it happens, most people first want to know how to feel better, then how to prevent a recurrence. – Penn State Health Milton S. Hershey Medical Center MedWire Announcements ISPOR Announces Key Leadership Appointments in Global Networks Group The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) recently announced the appointment of three leadership positions in its Global Networks Division. – International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Rajnish Mehrotra, MD, FASN to Lead the Clinical Journal of the American Society of Nephrology’s Incoming Editorial Team Rajnish Mehrotra, MD, FASN, begins his 6-year team as Editor-in-Chief of the Clinical Journal of the American Society of Nephrology (CJASN) on January 1, 2017, alongside an incoming editorial team of 17 highly accomplished nephrology researchers. – American Society of Nephrology (ASN) Embargo expired on 06-Jan-2017 at 17:00 ET Vincent Chan to Receive Distinguished Service Award Vincent W.S. Chan, MD, FRCPC, professor of Anesthesia at the University of Toronto, has been selected to receive ASRA's Distinguished Service Award. – American Society of Regional Anesthesia and Pain Medicine (ASRA) Fixing Failing Hearts: National Leaders to Convene at Heart Recovery “Think Tank” Can a failing heart recover? For many years, the answer to that question was unequivocally “No.” But as the University of Utah School of Medicine’s annual Utah Cardiac Recovery Symposium (U-CARS) will explore on Jan. 12-13, advances in treating... – University of Utah Health Sciences Nigel Sharrock to Receive Gaston Labat Award at ASRA in San Francisco Dr. Nigel Sharrock will present the prestigious Gaston Labat Award Lectureship on April 8th at the Excellence in ASRA Awards Luncheon, held in conjunction with the 42nd Annual Regional Anesthesiology and Acute Pain Medicine Meeting in San Francisco, ... – American Society of Regional Anesthesia and Pain Medicine (ASRA) APA Appoints Rose Sokol-Chang, PhD, Publisher of Journals The American Psychological Association has appointed Rose Sokol-Chang, PhD, as publisher of journals in its Office of Publications and Databases, charged with managing all the editorial, peer review and production functions of APA’s journals’ pro... – American Psychological Association (APA) Dr. Steven Schwarz Is the Recipient of the 2016 Murray Davidson Award Steven M. Schwarz, MD, FAAP, FACN, AGAF, professor of pediatrics at SUNY Downstate Medical Center, was honored with the prestigious Murray Davidson Award for 2016 by the American Academy of Pediatrics (AAP). – SUNY Downstate Medical Center Preventing Mortality After Myocardial Infarction The National Institutes of Health (NIH) is funding Canadian component of a study to determine the optimal amount of blood to transfuse in anemic patients who have suffered a myocardial infarction. – Universite de Montreal MedWire Higher Education Events Pandemic Preparedness in the Next Administration As the United States prepares for new leadership, global health thought leaders will convene January 10 to discuss ways the Trump administration can contribute to pandemic preparedness, global health security, and domestic readiness and resilience. – Georgetown University Medical Center